I've V12 too and running in 225/40/18 front and 255/35/18 rear (36 front and 40 psi rear).
The tire is very gripy in dry and wet condition
! I'm very happy with them ... Buuuuut ... I feel them a bit uncomfortable (vibrations from 80 to 95 and before or after nothing, very smooth and comfortable
). That the only drawback for me !
I drove a bit hard this week with them, hardly cornering on dry road and they had a perfect grip (I think equal or better than my previous Pirelli PZero in RF).